1.

New England Revolution
 vs. Portland Timbers

March 24, 2012
Saturday, 4:00 pm

 2.

New England Revolution
 vs. DC United

April 14, 2012
Saturday, 4:00 pm

 3.

New England Revolution
 vs. Colorado Rapids

May 2, 2012
Wednesday, 8:00 pm

 4.

New England Revolution
 vs. Vancouver Whitecaps

May 12, 2012
Saturday, 7:30 pm

 5.

New England Revolution
 vs. Houston Dynamo

May 19, 2012
Saturday, 7:30 pm

 6.

New England Revolution
 vs. Chicago Fire

June 2, 2012
Saturday, 7:30 pm

 7.

New England Revolution
 vs. Columbus Crew

June 16, 2012
Saturday, 7:30 pm

 8.

New England Revolution
 vs. Seattle Sounders FC

June 30, 2012
Saturday, 7:30 pm

 9.

New England Revolution
 vs. New York Red Bulls

July 8, 2012
Sunday, 7:00 pm

 10.

New England Revolution
 vs. Toronto FC

July 14, 2012
Saturday, 7:30 pm

 11.

New England Revolution
 vs. Sporting Kansas City

August 4, 2012
Saturday, 7:30 pm

 12.

New England Revolution
 vs. Montreal Impact

August 12, 2012
Sunday, 7:00 pm

 13.

New England Revolution
 vs. Chivas USA

August 29, 2012
Wednesday, 8:00 pm

 14.

New England Revolution
 vs. Philadelphia Union

September 1, 2012
Saturday, 7:30 pm

 15.

New England Revolution
 vs. Columbus Crew

September 5, 2012
Wednesday, 8:00 pm

 16.

New England Revolution
 vs. New York Red Bulls

September 22, 2012
Saturday, 7:30 pm

 17.

New England Revolution
 vs. Chicago Fire

October 20, 2012
Saturday, 7:30 pm