1.

Seattle Sounders FC
 vs. Houston Dynamo

March 23, 2012
Friday, 7:00 pm

 2.

Seattle Sounders FC
 vs. San Jose Earthquakes

March 31, 2012
Saturday, 7:00 pm

 3.

Seattle Sounders FC
 vs. Colorado Rapids

April 14, 2012
Saturday, 1:00 pm

 4.

Seattle Sounders FC
 vs. Los Angeles Galaxy

May 2, 2012
Wednesday, 7:00 pm

 5.

Seattle Sounders FC
 vs. Philadelphia Union

May 5, 2012
Saturday, 1:00 pm

 6.

Seattle Sounders FC
 vs. Real Salt Lake

May 12, 2012
Saturday, 7:00 pm

 7.

Seattle Sounders FC
 vs. Columbus Crew

May 23, 2012
Wednesday, 7:00 pm

 8.

Seattle Sounders FC
 vs. Sporting Kansas City

June 20, 2012
Wednesday, 7:00 pm

 9.

Seattle Sounders FC
 vs. Colorado Rapids

July 7, 2012
Saturday, 8:00 pm

 10.

Seattle Sounders FC
 vs. Los Angeles Galaxy

August 5, 2012
Sunday, 7:00 pm

 11.

Seattle Sounders FC
 vs. Vancouver Whitecaps

August 18, 2012
Saturday, 1:00 pm

 12.

Seattle Sounders FC
 vs. Chivas USA

September 8, 2012
Saturday, TBA

 13.

Seattle Sounders FC
 vs. San Jose Earthquakes

September 23, 2012
Sunday, 7:00 pm

 14.

Seattle Sounders FC
 vs. Portland Timbers

October 7, 2012
Sunday, 6:00 pm

 15.

Seattle Sounders FC
 vs. Real Salt Lake

October 17, 2012
Wednesday, TBA

 16.

Seattle Sounders FC
 vs. FC Dallas

October 21, 2012
Sunday, 6:00 pm